.png)
___________
RTSM implementations have traditionally followed a fairly rigid and sequential process: sponsors and RTSM teams spend a lot of time defining requirements on paper, those requirements are translated into configuration layered as needed with custom code, and the first meaningful look at the system usually happens only after development is complete. It’s an approach that works, but it often leads to long timelines,multiple cycles of clarification, and the occasional disconnect between whatthe study team intended and how the RTSM actually functions.
Instead of the traditional modelwhere requirements and system build happen in separate phases, Elosity allowsboth to occur in tandem. Its guided design interface and configurability letEndpoint Business Solutions Architects build the RTSM directly as they reviewthe protocol. This means sponsors are seeing the in-progress build muchearlier, often beginning at the very first design discussions, and the entireprocess becomes more collaborative, transparent, and aligned with how studyteams actually think about their workflows.
In a standard RTSM build, most ofthe early effort focuses on translating the protocol into detailed requirements documents. These documents are essential, but they can introduce challenges, especially when different teams interpret details slightly differently or when a concept makes sense on paper but looks or behaves differently once it’s in the RTSM. That dynamic can slow things down, and in some cases, it forces teams torevisit decisions later in the implementation process.
Elosity shifts this dynamic byletting teams see the RTSM as it’s being built. The Endpoint Business SolutionsArchitect works directly within a step-by-step configuration flow, and asfoundational elements like treatment arms, kit types, initial cohorts, andstudy-specific data elements are defined, they naturally feed into latercomponents such as visit schedules, transactions, and dispensation rules. Theresult is that decisions are grounded in how the system will actually function, not just how they sound in a document.
One of the biggest advantages ofthis approach is that study teams get to interact with the RTSM much earlierthan they’ve been able to in the past. They aren’t just reviewing textdescriptions of what the system will do; they can actually see it, eitherthrough design interface visualizations or through the Live Preview, whichreflects a fully functioning version of the study as it’s being configured.
As the build progresses, sponsorscan receive read-only access to the development environment. With dummy kitsand randomization lists loaded, teams can walk through complete patient andinventory workflows, view the system from multiple user roles, and understandhow blinding and role-based access configurations are operating. This level ofearly visibility leads to much clearer decision making, better alignment acrossteams, and more effective preparation for UAT.
Because Elosity is configuration-based,the reliance on technical development resources is significantly reduced. TheBusiness Solutions Architect manages the end-to-end build using the guidedinterface, which simplifies design conversations and removes many of the layersthat typically exist in custom-coded RTSM implementations. What would normallyrequire going back to technical teams to scope, code, and test can often beconfigured and reviewed live in a session.
This same benefit applies to studyintegrations. Elosity’s Integration Marketplace contains a library of integrationsthat are built once, validated, and made available for configuration acrossstudies. It removes a tremendous amount of friction by avoiding customizedintegration builds each time and gives study teams a clear, consistent approachto connecting RTSM with systems like EDC, inventory management, temperatureexcursion monitoring, forecasting, and ePRO/eCOA.
Protocol amendments are a realityfor almost every trial, and they’ve historically been one of the most time-consumingparts of RTSM maintenance. Elosity’s configuration driven approach and built-inversion control significantly improve this experience. Production versions canbe brought back into the development environment without interrupting ongoingstudy operations, updated using the same guided configuration interface used inthe initial build, and reviewed with complete transparency. Because changes don’trequire new code, even for integration modifications, amendment timelines shiftfrom months to days or weeks, depending on the complexity of the update.
This makes the amendment processmore predictable and far less disruptive for sponsors and operational teams.
It’s worth noting that Elosity wasn’t built in a vacuum. Endpoint’s team has more than 15 years of experience delivering RTSM solutions across thousands of trials, and that experience directly shaped the platform. The same people who influenced the design of Elosity - the ones who understand the nuance of randomization, supply strategy, operational workflows, and integrations - are the ones guiding study teams through implementation.
This combination of sophisticatedtools and experienced people is what allows the agile model to really work. Theplatform provides the flexibility, transparency, and speed, and the teamensures every design decision is grounded in RTSM best practices and alignedwith the study’s needs.
Elosity brings togetherconfiguration-based design, real-time system visibility, reusable integrations,and a far more agile amendment process. Study teams understand their systemearlier, make decisions with greater clarity, and move through the build andamendment cycles more efficiently, all while reducing reliance on technicalteams.
For modern clinical trials, especiallythose with adaptive components or evolving protocols, this level of agilityisn’t just helpful. It’s essential.
If you’re preparing for anupcoming study and want a more interactive and flexible RTSM experience, we’dbe glad to show you how Elosity can support your goals.
A Next Generation Approach to Study Design and Delivery

Agentic AI as a Catalyst for Clinical Innovation

Explore how PULSE® is redefining RTSM with speed, flexibility, and AI-powered insights.